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Shendure Lab
Developing new technologies and methods for genetics, genomics, and molecular biology for next-generation DNA sequencing to measure biological phenomena.
The Seattle Hub for Synthetic Biology is a collaboration between Allen Institute, Chan Zuckerberg Initiative and the University of Washington.
Goals and Approach
The Shendure Lab is part of the Howard Hughes Medical Institute and the Department of Genome Sciences at the University of Washington (Seattle, WA). The mission of our lab is to develop and apply new technologies and methods for genetics, genomics and molecular biology. Most of our work exploits next-generation DNA sequencing which is effectively emerging as a broadly enabling microscope for the measurement of biological phenomena. Our ongoing work generally falls into six areas. These are listed below as links to representative publications in each area.
- Developing New Molecular Methods
- Genomic Approaches to Developmental Biology
- Massively Parallel Functional Genomics
- Translating Genomics to the Clinic
- Genetic Basis of Human Disease
- Genome Sequencing Technologies
Research Details
- We aim to record molecular events during human tissue development onto the genome using DNA typewriter. This will uncover cellular histories that are critical for dynamic developmental processes.